Sabotage by the brain’s supporting cells helps fuel neurodegeneration
نویسندگان
چکیده
منابع مشابه
Grafting mouse brains: from neurocarcinogenesis to neurodegeneration.
When I received a telephone call in early July 1998 breaking the news that I was to be awarded the EMBO gold medal, I could not help but remember the awe with which I had been looking upon my then-supervisor Erwin Wagner a decade ago, when he was awarded the very same prize. Since I was asked to write an autobiographical review of my scientific activities, I dug out the medal review by Erwin Wa...
متن کاملThe relation between inflammation and neurodegeneration in multiple sclerosis brains
Some recent studies suggest that in progressive multiple sclerosis, neurodegeneration may occur independently from inflammation. The aim of our study was to analyse the interdependence of inflammation, neurodegeneration and disease progression in various multiple sclerosis stages in relation to lesional activity and clinical course, with a particular focus on progressive multiple sclerosis. The...
متن کاملPreparation of Nitrogen-Doped Graphene By Solvothermal Process as Supporting Material for Fuel Cell Catalysts
Development of efficient electrocatalysts for oxygen reduction reaction (ORR) is one of the most important issues for optimizing the performance of fuel cells and metal-air batteries. The introduction of nitrogen into carbon nanostructures has created new pathways for the development of non-precious electrocatalysts in fuel cells. In this work, nitrogen-doped graphene (NG) was synthesized by a ...
متن کاملDon’t Lose Sleep Over Neurodegeneration-It Helps Clear Amyloid Beta
Xie et al. in their article entitled “sleep drives metabolite clearance from the adult brain” in Science (342: 373–377) (1), provide an important insight into the potential physiology behind the restorative and homeostatic nature of sleep, a basic requirement for normal brain function. This study, utilizing a mouse model explores the clearance of peptides such as amyloid beta, which is implicat...
متن کاملSelf - Sabotage ∗
We analyze the incentives of a vertically-integrated producer (VIP) to engage in “self-sabotage”. Self-sabotage occurs when a VIP intentionally increases its upstream costs and/or reduces the quality of its upstream product. We identify conditions under which self-sabotage is profitable for the VIP even though it raises symmetrically the cost of the upstream product to all downstream producers ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 2018
ISSN: 0028-0836,1476-4687
DOI: 10.1038/d41586-018-04988-3